Milan, 22 March 2016 – New technology in the medical field: the researchers of ‘ European Institute of Oncology, thanks to a grant of 150 thousand euro provided by AIRC, have developed a tool very specifically, a ‘nose’ electronic capable of analyzing the breath of a person and find a any lung cancer at an early stage. The cost? And ‘content, 1200 € in all.
The announcement came from Lorenzo Spaggiari (University of Milan), Director of Thoracic Surgery and head of the IEO Lung Program, adding that the goal is “to give checkmate to lung cancer diagnosticandolo in time, when the healing ability can reach 80% “. The results of the study on the ‘nose’ Electronic – developed in collaboration with the Tor Vergata University of Rome – were published in the Journal of Breath Research. Of a total of 146 workers, including 70 diagnosed with cancer and 76 without signs of disease, the device was able to discriminate the breath of who was getting sick of lung cancer than those who did not run any risk, with a accuracy of 90%. The researchers pointed out that a device of this type, if the results are confirmed by further research, could serve to make a first low-cost screening of people at risk, and then subjected to low-dose Tac those who test positive.
This ‘nose’ electronic developed in IEO is based on the fact that the cancer cell emits specific volatile organic compounds (VOC), which are into the ‘beds’ eight sensors, which emettonovibrazioni that play as particular fingerprint on a computer, that is how it functions in a graph. The patient must do is blow into a plastic tube (similar to that used to detect the rate of alcohol in the breath of motorists) connected to two containers, for the part ‘high’ EBC and the deepest part, alveolar . The two containers are connected to the instrument, in turn connected to the PC, which in a few minutes gives the response. According Spaggiari, it comes to an analysis at a low cost in an examination which, once the results are confirmed by further studies, it could be run by the family doctor, to leave at a more expensive Tac if further investigation.
“the next step – explained Roberto Gasparri, thoracic surgeon IEA and first author of the study – will be to study together the three biological fluids of the body (exhaled, blood and urine) to find out in an even more accurate lung cancer at an early stage “. This research will use a ‘nose’ more technological (cost 7000 EUR), equipped with 10 sensors (instead of 8), plus a specific microsensor eleventh to ‘read VOC urine. And in this trial will tile the analysis of the ‘microRNA blood, ie of DNA fragments that the tumor still in formation can release in the blood and that therefore predict the presence of early-stage disease. In particular, the sensor urine was studied by the engineers of ‘IEO after a trial lasting six months, which (with the collaboration of the Institute of Veterinary Medicine of the’ University) involved a number of dogs, that have proven able to detect the presence of lung cancer simply by sniffing and identifying VOCs in the urine.
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